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Puppies Flea Allergies              Kittens Leukemia
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Puppies

We would like to congratulate you on the acquisition on your new puppy. Owning a dog can be an extremely rewarding experience, but it also carries with it quite a bit of responsibility. We hope this document will give you the information needed to make some good decisions regarding your puppy.

First, let us say that we are grateful that you have chosen us to help you with your puppy's health care. If you have questions concerning any subject related to your puppy's health, please feel free to call our hospital. Our entire professional staff is willing and happy to help you.

Puppy Playing

Stimulating play is important during the first week. Stalking and pouncing are important play behaviors in puppies and are necessary for proper muscular development. If given a sufficient outlet for these behaviors with toys, your puppy will be less likely to use family members for these activities. The best toys are light weight and movable. These include wads of paper and rubber balls. Any toy that is small enough to be swallowed should be avoided.

Discipline

Disciplining a young puppy may be necessary if its behavior threatens people or property, but harsh punishment should be avoided. Hand clapping and using shaker cans or horns can be intimidating enough to inhibit undesirable behavior. However, remote punishment is preferred. Remote punishment consists of using something that appears unconnected to the punisher to stop the problem behavior. Examples include using spray bottles, throwing objects in the direction of the puppy to startle (but not hit) it, and making loud noises. Remote punishment is preferred because the puppy associates punishment with the undesirable act and not with you.

Vaccinations

There are many diseases that are fatal to dogs. Fortunately, we have the ability to prevent many of these by the use of very effective vaccines. In order to be effective, these vaccines must be given as a series of injections. Ideally, they are given at about 6-8, 12, and 16 weeks of age, but this schedule may vary somewhat depending on several factors.

The routine vaccination schedule will protect your puppy from five diseases: distemper, hepatitis, parainfluenza virus, parvovirus, and rabies. The first four are included in one injection that is given at 6-8, 12, and 16 weeks old. Rabies vaccine is given at 16 weeks of age. There are two other optional vaccinations that are appropriate in certain situations. Your puppy should receive kennel cough vaccine (Intra Trac II) if a trip to a boarding kennel is likely or if it will be placed in a puppy training class. Lyme vaccine is given to dogs that are exposed to ticks because Lyme Disease is transmitted by ticks. Please advise us of these needs on your next visit.

Why the Series of Vaccinations

When the puppy nurses its mother, it receives a temporary form of immunity through its mother's milk. This immunity is in the form of proteins called antibodies. For about 24-48 hours after birth, the puppy's intestine allows absorption of these antibodies directly into the blood stream. This immunity is of benefit during the first few weeks of the puppy's life, but, at some point, this immunity fails and the puppy must be able to make its own long-lasting immunity. Vaccinations are used for this purpose. As long as the mother's antibodies are present, vaccinations do not have a chance to stimulate the puppy's immune system. The mother's antibodies interfere by neutralizing the vaccine.

Many factors determine when the puppy will be able to respond to the vaccinations. These include the level of immunity in the mother dog, how much antibody has been absorbed, and the number of vaccines given to the puppy. Since we do not know when an individual puppy will lose the short-term immunity, we give a series of vaccinations. We hope that at least two of these will fall in the window of time when the puppy has lost immunity from its mother but has not yet been exposed to disease. A single vaccination, even if effective, is not likely to stimulate the long-term immunity that is so important.

Rabies vaccine is an exception to this, since one injection given at the proper time is enough to produce long-term immunity.

Intestinal Worms

Intestinal parasites are common in puppies. Puppies can become infected with parasites before they are born or later through their mother's milk. The microscopic examination of a stool sample will usually help us to determine the presence of intestinal parasites. We recommend this exam for all puppies. If we can not get a stool sample, please bring one at your earliest convenience. Even if we do not get a stool sample, we recommend the use of Drontal, a deworming product that is safe and effective against several of the common worms of the dog. It is given now and repeated in about 3 weeks. Food should not be withheld before or after administering the tablet. It is important that it be repeated in about 3 weeks because the deworming medication only kills the adult worms. Within 3-4 weeks, the larval stages will have become adults and will need to be treated. Dogs remain susceptible to reinfection with hookworms and roundworms. Periodic deworming throughout the dog's life may be recommended for dogs that go outdoors.

Tapeworms are the most common intestinal parasite of dogs. Puppies become infected with them when they swallow fleas; the eggs of the tapeworm live inside the flea. When the dog chews or licks its skin as a flea bites, the flea may be swallowed. The flea is digested within the dog's intestine; the tapeworm hatches and then anchors itself to the intestinal lining. Therefore, exposure to fleas may result in a new infection; this can occur in as little as two weeks.

Dogs infected with tapeworms will pass small segments of the worms in their stool. The segments are white in color and look like grains of rice. They are about 1/8 inch (3 mm) long and may be seen crawling on the surface of the stool. They may also stick to the hair under the tail. If that occurs, they will dry out, shrink to about half their size, and become golden in color.

Tapeworm segments do not pass every day or in every stool sample; therefore, inspection of several consecutive bowel movements may be needed to find them. We may examine a stool sample in our office and not find them, then you may find them the next day. If you find them at any time, please notify us so we may provide the appropriate drug for treatment.

Heartworms

Heartworms are important parasites, especially in certain climates. They can live in your dog's heart and cause major damage to the heart and lungs. Heartworms are transmitted by mosquitoes so your dogs does not have to be in contact with another dog to be exposed. Fortunately, we have drugs that will protect your dog from heartworms. These drugs are very safe and very effective if given regularly. One product, Filarabits Plus , is a chewable tablet that your dog should eat like a treat; it is given daily. Three others, Heartgard , Interceptor , and Revolution are tablets that are given only once monthly. We recommend the product that is most likely to be given on a regular basis, either daily or monthly. Be aware that having a long haircoat or staying primarily indoors does not protect a dog against heartworm infection.

Heartworm preventatives are dosed according to your dog's weight. As the weight increases, the dosage should also increase. Please note the dosing instructions on the package. These products are very safe. You could overdose your dog by two or three times the recommended dose without causing harm. Therefore, it is always better to overdose rather than underdose.

Food for Puppies

Diet is extremely important in the growing months of a dog's life, and there are two important criteria that should be met in selecting food for your puppy. We recommend a NAME-BRAND FOOD made by a national dog food company (not a generic or local brand), and a form of food MADE FOR PUPPIES. This should be fed until your puppy is about 12-18 months of age, depending on its size. We recommend that you only buy food that has the AAFCO certification. Usually, you can find this information very easily on the label. AAFCO is an organization that oversees the entire pet food industry. It does not endorse any particular food, but it will certify that the food has met the minimum requirements for nutrition. Most of the commercial pet foods will have the AAFCO label. Generic brands often do not have it.

Feeding a dry, canned, or semi-moist form of dog food is acceptable. Each has advantages and disadvantages. Dry food is definitely the most inexpensive. It can be left in the dog's bowl without drying. The good brands of dry food are just as nutritious as the other forms. As a rule, most veterinarians will recommend dry food for your puppy.

Semi-moist and canned foods are also acceptable. However, both are considerably more expensive than dry food. They often are more appealing to the dog's taste; however, they are not more nutritious. If you feed a very tasty food, you are running the risk of creating a dog with a finicky appetite. In addition, the semi-moist foods are high in sugar.

Table foods are not recommended. Because they are generally very tasty, dogs will often begin to hold out for these and not eat their well-balanced dog food. If you choose to give your puppy table food, be sure that at least 90% of its diet is good quality commercial puppy food.

We enjoy a variety of things to eat in our diet. However, most dogs actually prefer not to change from one food to another unless they are trained to do so by the way you feed them. Do not feel guilty if your dog is happy to just eat one food day after day, week after week.

Commercials for dog food can be very misleading. If you watch carefully you will notice that many commercials promote dog food on one basis, TASTE. Nutrition is rarely mentioned. Most of the "gourmet" foods are marketed to appeal to owners who wants the best for their dogs; however, they do not offer the dog any nutritional advantage over a good quality dry food, and they are far more expensive. If your dog eats a gourmet food very long, it will probably not be happy with other foods. If it needs a special diet due to a health problem later in life, it is very unlikely to accept it. Therefore, we do not encourage feeding gourmet dog foods.

In addition to table foods, it is also important that you not give certain other things to dogs. Bones of birds (chicken, turkey, etc.) are hollow and splinter easily producing very sharp pointed pieces of bones. These can easily pierce the esophagus, stomach, and intestines resulting in peritonitis and death.

Feeding Schedules

There are several "right" ways to feed puppies. The most popular method is commonly called "meal feeding". This means that the puppy is fed at specific times of the day. A measured amount of food should be offered four times per day for 5-12 week old puppies. What is not eaten within 30 minutes is taken up. If the food is eaten within 3-4 minutes, the quantity is probably not sufficient. Puppies fed in this manner generally begin to cut themselves out of one of those meals by 3-4 months of age and perhaps another one later. If a meal is ignored for several days, it should be discontinued.

"Free choice feeding" means that food is available at all times. This works well with dry foods and for some dogs. However, other dogs tend to overeat and become obese. If there are signs of weight gain after the optimal weight is reached, this method of feeding should be discontinued.

Housebreaking

Housebreaking should begin as soon as your puppy enters his new home. How long the training must continue depends on both the puppy and you. Some pups learn sooner than others. Your dog wants to please you. But a puppy's memory is short, so your patience is important. A home with a badly trained puppy is not a happy home for you or the puppy.

-The puppy's bed may be a box, open at one end and slightly larger than the puppy. If the bed is too large, the puppy may defecate or urinate in a corner rather than go outside. If the bed is smaller, the puppy will do its "business" outside rather than soil its bed.

-Enclose the bed in a small area, such as a laundry room. Cover this area with newspapers to be used at night, or when your pup is left unsupervised.

-The secret to housebreaking is a scent post. A scent post is created when your puppy has an "accident." The problem becomes one of locating the scent post in the place you want it.

-To create a scent post, leave a smear of stool from the last "accident" or wet paper on the clean paper in the place you want it, and coax or scoot the puppy to that area. The same is true of an outside scent post, but without the paper, in an out-of-the-way place in the yard. This will solve the "mine-field" problem.

-The first thing in the morning, the puppy should be scooted to the scent post. This is so he can learn his way to the door and the scent post. Let him sniff about. The moment he has relieved himself, pat him on the head and immediately bring him into the house. Do not let him play about. The toilet period and play period should be definitely separate in the puppy's routine.

-The puppy should then be fed. In a short while the puppy will become uneasy and walk in circles sniffing at the floor. The puppy should then be scooted and coaxed to the scent post as quickly as possible.

-This routine should be repeated every hour or two throughout the day, especially after meals and naps.

-When the puppy is taken out to play, it is wise to leave the house by another door and avoid taking him near his scent post. Never play with your pup until after he has been taken out and has eliminated.

-There will of course be some "accidents" in the house. Never let one of these slip by unnoticed; punishment five minutes after the offense is too late. Scold (not whip) the puppy and rush him to the scent post. Then scrub the area of mishap thoroughly until all odor is gone. Sprinkle the area with red pepper or vinegar.

-Positive reinforcement of proper urine and bowel habits is just as important as properly applied discipline. When your puppy urinates or defecates in the correct place, spend several minutes stroking and praising him.

Socialization of Puppies

The Socialization Period for dogs is between 4 and 12 weeks of age. During that time, the puppy is very impressionable to social influences. If it has good experiences with men, women, children, cats, other dogs, etc., it is likely to accept them throughout life. If the experiences are absent or unpleasant, it may become apprehensive or adverse to any of them. Therefore, during the period of socialization, we encourage you to expose your dog to as many types of social events and influences as possible.

Three Curious Things about Puppies

Puppies may be observed to make unusual sounds or movements during their sleep. This is called "cactivated sleep". It probably occurs because your puppy is dreaming and trying to participate in the dream. This behavior lasts a few months but rarely continues into adulthood.

Puppies also have "puppy breath". There is a characteristic smell about a puppy's breath. It is not particularly offensive or desirable. It is much like the smell of a new car. It is present a few weeks then disappears.

Puppies also frequently have episodes of hiccups. They may occur for 10-20 minutes at a time then spontaneously disappear. They are probably related to swallowing of air when eating and do not produce any significant distress to your dog. They will stop as your puppy gets a little older.

Flea Control

Fleas do not stay on your puppy all of their time; occasionally, they will jump off and seek another host. Therefore, it is important to kill fleas on your new puppy before they can become established in your house. Many of the flea control products that are safe on adult dogs are not safe for puppies less than 4 months of age. Be sure that any flea product you use is labeled safe for puppies.

If you use a flea spray, your puppy should be sprayed lightly. Flea and tick dip is not recommended for puppies unless they are at least 4 months of age. Remember, not all insecticides that can be used on adult dogs are safe for puppies.

There is a trick to spraying a puppy that will make the outcome safer and more successful. When a puppy is sprayed, the fleas tend to run away from the insecticide. If you spray the body first, many fleas will run to the head where they are very difficult to kill. The best method is to spray a cotton ball then use that to wipe the flea spray onto the puppy's face, from the nose to the level of the ears. That will keep you from getting it in the eyes and will cause the fleas to run toward the body. Wait about 2 minutes, then spray the back of the head and the body. Leave the spray on for about 3 minutes, then wipe off the excess. This will permit you to kill the most fleas while putting the least amount of insecticide on the puppy.

There are four products that are given only once per month; some can be used in puppies as young as 6 weeks. Program is a tablet that causes the adult fleas to lay sterile eggs. It is very effective, but it does not kill adult fleas that usually live 2-3 months. Advantage , Frontline Top Spot , and Revolution are the monthly products that kill adult fleas. They are liquids that are applied to the skin at the base of the neck. They are very effective and easy to use.

Chewing

One of the characteristics of puppies is chewing. Puppies are trying their new teeth so chewing is a normal behavior. The puppy's baby teeth are present by about 4 weeks of age. They begin to fall out at 4 months of age and are replaced by the adult (permanent) teeth by about 6 months of age. Therefore, chewing is a puppy characteristic that you can expect until about 6-7 months of age. It is important that you do what you can to direct your puppy's chewing toward acceptable objects. You should provide items such as rawhide chew bones, nylon chew bones, and other chew toys so other objects are spared.

Trimming Toenails

Puppies have very sharp toenails. They can be trimmed with your regular finger nail clippers or with nail trimmers made for dogs and cats. If you take too much off the nail, you will get into the quick; bleeding and pain will occur. If this happens, neither you nor your dog will want to do this again. Therefore, a few points are helpful:

1. If your dog has clear or white nails, you can see the pink of the quick through the nail. Avoid the pink area, and you should be out of the quick.

2. If your dog has black nails, you will not be able to see the quick so only cut 1/32" (1 mm) of the nail at a time until the dog begins to get sensitive. The sensitivity will usually occur before you are into the blood vessel. With black nails, it is likely that you will get too close on at least one nail.

3. If your dog has some clear and some black nails, use the average clear nail as a guide for cutting the black ones.

4. When cutting nails, use sharp trimmers. Dull trimmers tend to crush the nail and cause pain even if you are not in the quick.

5. You should always have styptic powder available. This is sold in pet stores under several trade names, but it will be labeled for use in trimming nails.

Ear Mites

Ear mites are tiny parasites that live in the ear canal of dogs (and cats). The most common sign of ear mite infection is scratching of the ears. Sometimes the ears will appear dirty because of a black material in the ear canal; this material is sometimes shaken out. The instrument we use for examining the ear canals, an otoscope, has the necessary magnification to allow us to see the mites. Sometimes, we can find the mites by taking a small amount of the black material from the ear canal and examining it with a microscope. Although they may leave the ear canals for short periods of time, they spend the vast majority of their lives within the protection of the ear canal. Transmission generally requires direct ear-to-ear contact. Ear mites are common in litters of puppies if their mother has ear mites.

Ear infections may also cause the production of a dark discharge in the ear canals. It is important that we examine you puppy to be sure the black material is due to ear mites and not infection. Please do not ask us to just dispense medication without having the opportunity to make an accurate diagnosis.

Spaying Females

Spaying offers several advantages. The female's heat periods result in about 2-3 weeks of vaginal bleeding. This can be quite annoying if your dog is kept indoors. Male dogs are attracted from blocks away and, in fact, seem to come out of the woodwork. They seem to go over, around, and through many doors or fences. Your dog will have a heat period about every 6 months.

Spaying is the removal of the uterus and the ovaries. Therefore, heat periods no longer occur. In many cases, despite of your best effort, the female will become pregnant; spaying prevents unplanned litters of puppies.

It has been proven that as the female dog gets older, there is a significant incidence of breast cancer and uterine infections if she has not been spayed. Spaying before she has any heat periods will virtually eliminate the chance of either. If you do not plan to breed your dog, we strongly recommend that she be spayed before her first heat period. This can be done anytime after she is 6 months old.

Neutering Males

Neutering offers several advantages. Male dogs are attracted to a female dog in heat and will climb over or go through fences to find her. Male dogs are more aggressive and more likely to fight, especially with other male dogs. As dogs age, the prostate gland frequently enlarges and causes difficulty urinating and defecating. Neutering will solve, or greatly help, all of these problems that come with owning a male dog. The surgery can be performed any time after the dog is 6 months old.

Breeding

If you plan to breed your dog, she should have at least one or two heat periods first. This will allow her to physically mature allowing her to be a better mother without such a physical drain on her. We do not recommend breeding after 5 years of age unless she has been bred prior to that. Having her first litter after 5 years of age increases the risk of problems during the pregnancy and/or delivery. Once your dog has had her last litter, she should be spayed to prevent the reproductive problems older dogs have.

Pet Identification

The latest in pet retrieval is microchipping. This tiny device is implanted with a needle so the process is much like getting an injection. Our scanner can detect these chips; humane societies and animal shelters across the country also have scanners. A national registry permits the return of microchipped pets throughout the United States and Canada. We recommend it.

Emergency Tips

There are several emergency situations that are common. The following recommendations could be valuable for you to know.

Hit by car. Let your dog stand up by itself. If it cannot, transfer it to a hard board for transporting. Apply pressure to wounds with soft gauze. Keep your dog warm to prevent shock. An injured dog may bite, even people that it knows very well. Use caution for the safety of both you and your dog. Seek medical attention quickly.

Overheating. If you suspect you dog has collapsed from heat stress, start to cool it down with a cool water bath, fans, cold compresses, or ice packs. Seek medical attention immediately.

Minor Burns. Treat with cool water and seek medical attention.

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Heartworm Disease in Dogs

Heartworm disease (dirofilariasis) is a serious and potentially fatal disease in dogs. It is caused by a worm called Dirofilaria immitis.

Heartworms are found in the heart and large adjacent vessels of infected dogs. The female worm is 6 to 14 inches (15 to 36 cm) long and 1/8 inch (5 mm) wide; the male is about half the size of the female. One dog may have as many as 300 worms.

How Heartworms Get into the Heart

Adult heartworms live in the heart and pulmonary arteries of infected dogs. They have been found in other areas of the body, but this is unusual. They survive up to 5 years and, during this time, the female produces millions of young (microfilaria). These microfilaria live in the bloodstream, mainly in the small blood vessels. The immature heartworms cannot complete the entire life cycle in the dog; the mosquito is required for some stages of the heartworm life cycle. The microfilaria are therefore not infective (cannot grow to adulthood) in the dog--although they do cause problems.

As many as 30 species of mosquitoes can transmit heartworms. The female mosquito bites the infected dog and ingests the microfilariae during a blood meal. The microfilariae develop further for 10 to 30 days in the mosquito and then enter the mouthparts of the mosquito. The microfilariae are now called infective larvae because at this stage of development, they will grow to adulthood when they enter a dog. The mosquito bites the dog where the haircoat is thinnest. However, having long hair does not prevent a dog from getting heartworms.

When fully developed, the infective larvae enter the bloodstream and move to the heart and adjacent vessels, where they grow to maturity in 2 to 3 months and start reproducing, thereby completing the full life cycle.

Geography

Canine heartworm disease occurs all over the world. In the United States, it was once limited to the south and southeast regions. However, the disease is spreading and is now found in most regions of the United States and Canada, particularly where mosquitoes are prevalent.

Contagion

The disease is not spread directly from dog to dog. An intermediate host, the mosquito, is required for transmission. Spread of the disease therefore coincides with the mosquito season. The number of dogs infected and the length of the mosquito season are directly correlated with the incidence of heartworm disease in any given area.

It takes a number of years before dogs show outward signs of infection. Consequently, the disease is diagnosed mostly in 4 to 8 year old dogs. The disease is seldom diagnosed in a dog under 1 year of age because the young worms (larvae) take up to 7 months to mature following establishment of infection in a dog.

Effects on the Dog

Adult worms: Adult worms cause disease by clogging the heart and major blood vessels leading from the heart. They interfere with the valve action in the heart. By clogging the main blood vessels, the blood supply to other organs of the body is reduced, particularly the lungs, liver and kidneys, leading to malfunction of these organs.

Most dogs infected with heartworms do not show any signs of disease for as long as 2 years. Unfortunately, by the time signs are seen, the disease is well advanced. The signs of heartworm disease depend on the number of adult worms present, the location of the worms, the length of time the worms have been present, and the degree of damage to the heart, lungs, liver, and kidneys from the adult worms and the microfilariae.

The most obvious signs are: a soft, dry, chronic cough, shortness of breath, weakness, nervousness, listlessness, and loss of stamina. All of these signs are most noticeable following exercise, when some dogs may even faint.

Listening to the chest with a stethoscope will often reveal abnormal lung and heart sounds. In advanced cases, congestive heart failure may be apparent and the abdomen and legs will swell from fluid accumulation. There may also be evidence of weight loss, poor condition, and anemia.

Severely infected dogs may die suddenly during exercise or excitement.

Microfilariae (Young worms): Microfilariae circulate throughout the body but remain primarily in the small blood vessels. Because they are as wide as the small vessels, they may block blood flow in these vessels. The body cells being supplied by these vessels are deprived of the nutrients and oxygen normally supplied by the blood. The lungs and liver are primarily affected.

Destruction of lung tissue leads to coughing. Cirrhosis of the liver causes jaundice, anemia, and general weakness because this organ is essential in maintaining a healthy animal. The kidneys may also be affected and allow poisons to accumulate in the body.

Diagnosis

In most cases, diagnosis of heartworm disease can be made by a blood test that can be run in the veterinary hospital. Further diagnostic procedures are essential, in advanced cases particularly, to determine if the dog can tolerate heartworm treatment. Depending on the case, we will recommend some or all of the following procedures before treatment is started.

Serological test for antigens to adult heartworms: This is a test performed on a blood sample. It is the most widely used test because it detects antigens (proteins) produced by adult heartworms. It will be positive even if the dog does not have any microfilaria in the blood; this occurs about 20% of the time. Dogs with less than five adult heartworms will not have enough antigen to turn the test positive, so there may be some false negative results in early infections. Because the antigen detected is produced only by the female worm, a pure population of male heartworms will give a false negative, also. Therefore, there must be at least 5 female worms present for the most common test to be positive.

Blood test for microfilariae: A blood sample is examined under the microscope for the presence of microfilariae. If microfilariae are seen, the test is positive. The number of microfilariae seen gives us a general indication of the severity of the infection. However, the microfilariae are seen in greater numbers in the summer months and in the evening, so these variations must be considered. Approximately 20% of dogs do not test positive even though they have heartworms because of an acquired immunity to this stage of the heartworm. Because of this, the antigen test is the preferred test. Also, there is another microfilarial parasite which is fairly common in dogs; on the blood smear, these can be hard to distinguish from heartworm microfilariae.

Blood chemistries: Complete blood counts and blood tests for kidney and liver function may give an indirect indication of the presence of heartworm disease. These tests are also performed on dogs diagnosed as heartworm-infected to determine the function of the dog's organs prior to treatment.

Radiographs (X-rays): A radiograph of a dog with heartworms will usually show heart enlargement and swelling of the large artery leading to the lungs from the heart. These signs are considered presumptive evidence of heartworm disease. Radiographs may also reveal the condition of the heart, lungs, and vessels. This information allows us to predict an increased possibility of complications related to treatment.

Electrocardiogram: An electrocardiogram (EKG) is a tracing of the electric currents generated by the heart. It is most useful to determine the presence of abnormal heart rhythms.

Echocardiography (Sonogram): An echocardiogram allows us to see into the heart chambers and even visualize the heartworms themselves. Although somewhat expensive, this procedure can diagnose heartworms when other tests fail.

Treatment

There is some risk involved in treating dogs with heartworms, although fatalities are rare. In the past, the drug used to treat heartworms contained arsenic so toxic effects and reactions occurred somewhat frequently. Now a newer drug is available that does not have the toxic side effects of the old one. We are able to successfully treat more than 95% of dogs with heartworms.

We see some dogs with advanced heartworm disease. This means that the heartworms have been present long enough to cause substantial damage to the heart, lungs, blood vessels, kidneys, and liver. A few of these cases will be so far advanced that it will be safer to just treat the organ damage rather than risk treatment to kill the worms. Dogs in this condition are not likely to live more than a few weeks or months.

Treatment to kill adult worms: An injectable drug to kill adult heartworms is drug is given for two days. It kills the adult heartworms in the heart and adjacent vessels.

Complete rest essential after treatment: The adult worms die in a few days and start to decompose. As they break up, they are carried to the lungs, where they lodge in the small blood vessels and are eventually reabsorbed by the body. This is a dangerous period, and it is absolutely essential that the dog be kept quiet and not be allowed to exercise for 1 month following treatment. The first week after the injections is very critical because the worms are dying. A cough is noticeable for 7 to 8 weeks after treatment in many heavily infected dogs.

Prompt treatment is essential if the dog has a significant reaction in the weeks following the initial treatment, although such reactions are not common. If a dog shows loss of appetite, shortness of breath, severe coughing, coughing up blood, fever, and/or depression, you should notify us. Response to antibiotics, cage rest, and supportive care, such as intravenous fluids, is usually good in these cases.

Treatment to kill microfilaria: Approximately 1 month following treatment to kill the adults, the dog is returned to the hospital for administration of a drug to kill microfilariae. Your dog needs to stay in the hospital for the day. Seven to ten days later a test is performed to determine if microfilariae are present. If they have been all killed, the treatment is complete. If there are still some present in the blood, treatment for microfilariae is repeated.

In some cases, the heartworm infection is "occult," meaning that no microfilariae were present. In this case, a follow-up treatment at one month is not needed.

Other treatments: In dogs with severe heartworm disease, it may be necessary to treat them with antibiotics, special diets, diuretics to remove fluid accumulations, and drugs to improve heart function prior to treatment for the heartworms.

Dogs with severe heart disease may need lifetime treatment for the failing heart, even after the heartworms have been killed. This includes the use of diuretics, heart drugs, aspirin, and special low salt, low protein diets.

Response to treatment: Dog owners are usually pleasantly surprised at the change in their dog following treatment for heartworms, especially if the dog had been showing signs of heartworm disease. The dog has a renewed vigor and vitality, improved appetite, and weight gain.

Prevention

When a dog has been successfully treated for heartworms, you cannot sit back and relax because dogs can be reinfected. Therefore, it is essential to begin a heartworm prevention program. There are four drugs that can be used to prevent heartworm infection. Filaribits Plus is a daily, chewable tablet; two others, HeartGard and Interceptor , are chewable tablets that are given only once monthly. Revolution is a topical product that is applied once monthly. All four products are very safe and very effective. Their costs are similar. One of these should be started immediately after the treatment is completed.

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Flea Allergy in Dogs

One of the most common conditions affecting dogs is allergy. In the allergic state, the dog's immune system "overreacts" to foreign substances (allergens or antigens) to which it is exposed. These overreactions are manifested in three ways. The most common is itching of the skin, either localized (one area) or generalized (all over the dog). Another manifestation involves the respiratory system and may result in coughing, sneezing, and/or wheezing. Sometimes, there may be an associated nasal or ocular (eye) discharge. The third manifestation involves the digestive system, resulting in vomiting or diarrhea. The specific response that occurs is related to the type of allergy present.

Types of Allergy

There are five known types of allergies in the dog: contact, flea, food, bacterial, and inhalant. Each of these has some common expressions in dogs, and each has some unique features.

In spite of common belief, a normal dog experiences only minor skin irritation in response to flea bites. Even in the presence of dozens of fleas, there will be very little itching. On the other hand, the flea allergic dog has a severe, itch-producing reaction to flea bites. This occurs because the dog develops an allergic response to the flea's saliva. When the dog is bitten, flea saliva is deposited in the skin. Just one bite causes intense itching.

Clinical Signs

The dog's response to the intense itching is to chew, lick, or scratch. This causes hair loss and can lead to open sores or scabs on the skin, allowing a secondary bacterial infection to begin. The area most commonly involved is over the rump (just in front of the tail). This is probably because fleas find this part of the dog more desirable. Many flea-allergic dogs also chew or lick the hair off of their legs.

Treatment

The most important treatment for flea allergy is to get the dog away from all fleas. Therefore, strict flea control is the backbone of successful treatment. There are many products available for flea control, and many work in entirely different manners. In some cases, multiple products may be needed. Some are used on the dog and some in the dog's environment. Unfortunately, complete flea control is not always possible for dogs that live outdoors in warm and humid climates, where a new population of fleas can hatch out every 14-21 days.

Some dogs can be desensitized to the adverse effects of fleabites. Flea saliva extract (flea antigen) is injected into the dog in tiny amounts over a prolonged period of time. This is an attempt to reprogram the dog's immune system so it no longer over-reacts to fleabites. If successful, itching no long occurs or is less intense when the dog is bitten. However, this approach is only successful about 50-75% of the time.

When strict flea control is not possible, corticosteroids (or "cortisone" or "steroids") can be used to block the allergic reaction and give relief. This is often a necessary part of dealing flea allergy. Some dogs respond best to long-acting injections and other to oral medication. Dogs are more resistant to the side-effects of steroids than humans, but significant side-effects can occur. For this reason, the goal is to administer the smallest amount of steroid needed to keep the dog comfortable.

Some dogs develop a secondary bacterial infection in the skin. When this occurs, appropriate antibiotics must be used.

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Flea Control for Dogs

Successful flea control has two aspects. Fleas must be controlled on your dog, and fleas must be controlled in your dog's environment. Since cats and dogs share the same fleas, the presence of a cat in your dog's environment can make flea control much more difficult.

Diagnosis of Flea Infestation

When a dog is heavily infested with fleas, it is easy to find them. If the numbers are small, it is best to quickly turn your dog over and look on its belly. If you do not find them there, look on the back just in front of the tail. Be sure to part the hair and look at the level of the skin. When the numbers are very small, look for "flea dirt." Flea dirt is digested blood left behind by the fleas. Flea dirt is actually fecal matter from the flea. Finding flea dirt is a sure indication that fleas are present or have been present recently.

Flea dirt looks like pepper. It varies from tiny black dots to tubular structures about 1/32" (1/2 mm) long. If you are not sure it is flea dirt, put the suspected material on a light colored table top or counter top. Add one or two drops of water, and wait about 30 seconds. If it is flea dirt, the water will turn reddish brown as the blood residue goes into solution. Another trick is to put some of the material on a white paper towel and then wet the paper towel with water. A red stain will become apparent if you gently wipe the material across the surface of the paper towel.

Many people find tiny drops of blood in a dog's bedding or where the dog sleeps. This is usually flea dirt that was moistened, then dried. It leaves a reddish stain on the bedding material and is another sign that fleas are present.

Life Cycle of the Flea

To appreciate the complex issue of flea control, you must understand something about the flea's life cycle.

Although you are only able to see the adult flea, there are actually 4 stages of the life cycle. The adult flea constitutes only about 5% of the entire flea population if you take into account all four stages of the life cycle. Flea eggs are pearly white and about 1/32" (1/2 mm) in length. They are too small to see without magnification. Fleas lay their eggs on the dog, but the eggs do not stick to the dog's hair. Instead, they fall off into the dog's environment. The eggs make up 50% of the flea population. They hatch into larvae in 1 to 10 days, depending on temperature and humidity. High humidity and temperature favor rapid hatching.

Flea larvae are slender and about 1/8-1/4" (2 to 5 mm) in length. They feed on organic debris found in their environment and on adult flea feces, which is essential for successful development. They avoid direct sunlight and actively move deep into carpet fibers or under organic debris (grass, branches, leaves, or soil.) They live for 5 to 11 days before becoming pupae.

Moisture is essential for their survival; flea larvae are killed by drying. Therefore, it is unlikely that they survive outdoors in shade-free areas. Outdoor larval development occurs only where the ground is shaded and moist and where flea-infested pets spend a significant amount of time. This allows flea feces to be deposited in the environment. In an indoor environment, larvae survive best in the protected environment of carpet or in cracks between hardwood floors. They also thrive in humid climates.

Following complete development, the mature larvae produce a silk-like cocoon in which the next step of development, the pupa, resides. The cocoon is sticky, so it quickly becomes coated with debris from the environment. This serves to camouflage it. In warm, humid conditions, pupae become adult fleas in 5-10 days. However, the adults do not emerge from the cocoon unless stimulated by physical pressure, carbon dioxide, or heat.

Pre-emerged adult fleas can survive up to 140 days within the cocoon. During this time, they are resistant to insecticides applied to their environment. Because of this, adult fleas may continue to emerge into the environment for up to 3 weeks following insecticide application.

When the adult flea emerges from its cocoon, it immediately seeks a host because it must have a blood meal within a few days to survive. It is attracted to people and pets by body heat, movement, and exhaled carbon dioxide. It seeks light, which means that it migrates to the surface of the carpet so that it can encounter a passing host. Following the first blood meal, female fleas begin egg production within 36 to 48 hours. Egg production can continue for as long as 100 days, which means that a single flea can produce thousands of eggs.

This entire life cycle (adult flea >>> egg >>> larvae >>> pupa >>> adult) can be completed in 14-21 days with the proper temperature and humidity conditions. This adds to the problem of flea control.

If untreated, the female flea will continue to take blood for several weeks. During that time, she will consume about 15 times her body weight in blood. Although the male fleas do not take as much blood, they, too, contribute to significant blood loss. This can lead to the dog having an insufficient number of red blood cells, which is known as anemia. In young or debilitated dogs, the anemia may be severe enough to cause death.

Contrary to popular belief, most dogs have rather limited itching due to fleabites. However, many dogs become allergic to the saliva in the flea's mouth. When these dogs are bitten, intense itching occurs, causing the dog to scratch and chew on its skin.

Flea Control

Successful flea control must rid the dog of fleas and it must rid the dog's environment of fleas. In fact, environmental control as important as treatment of the dog. If your dog remains primarily indoors and you do not have other pets that come in from the outside, environmental control is relatively easy, especially with the advent of the new topical products (see below). However, the dog that goes outdoors frequently or stays outdoors presents a somewhat greater challenge and a few fleas may occasionally be seen indoors.

Many of the older insecticides (which have been the mainstay of flea control for years) have limited effectiveness against fleas because they are only effective for a few hours after application on the dog. Also, these are primarily geared to kill adult fleas. Flea powders, sprays, and shampoos will kill the fleas present on your dog at the time of application. However, most of these products have little or no residual effects, so the fleas that return to your dog from his environment are not affected. Thus, your dog may be covered with fleas within a day after having a flea bath or being sprayed or powdered.

However, there are some newer, more effective sprays that can be a valuable part of the overall treatment plan. They kill adult fleas rapidly and are safe enough to use daily, if necessary. Flea sprays containing insect growth regulators are helpful in managing the overall problem because they help to break the flea life cycle. Some of the newer sprays with growth regulators are not recommended for daily use; once weekly application is recommended. Always read the label when first using any new product on a dog. In general, flea sprays, collars, powders and dips have become less popular since the introduction of the newer products.

Newer Products

Four relatively new products have come onto the market in the last couple of years. The "flea pill" is an oral medication that is given to the dog once a month. This product, Program , does not kill adult fleas but is helpful in breaking the life cycle of the flea. When the female flea produces eggs, they are essentially "sterile" eggs and do not hatch. In effect, this product acts like a birth control product for the flea. Three new topical treatments are applied to the nape of the neck. They are Advantage , Frontline Top Spot , and Revolution . All are safe and very effective.

Environmental Control

The newer topical products do not require the aggressive environmental control that is necessary if only dips, sprays, or collars are used. This is one reason that they have become so popular with pet owners. Many people try the newest products for 1-2 weeks to see if they are adequate. Please consult with us about the requirements for your specific situation.

When environmental flea control is indicated, it must be directed at your house and your yard.

House. Even though fleas may be in your house, most people never see them. Fleas greatly prefer cats and dogs to people; they only infest humans when there has not been a cat or dog in the house for several days. (There are exceptions to this.) A professional exterminator may be called to treat your house or you may use a house fogger or a long-lasting spray. These foggers and sprays are very effective for adult fleas, but they will not kill adults that are still in their cocoon. You should purchase a fogger or a spray that kills the adult fleas and inhibits development of the eggs and larvae. In climates with extended warm temperatures and high humidity, it may be necessary to treat two or three times with a 30-day residual product before all stages of the fleas are removed from the house. The second treatment is most effective if it is done 2 weeks after the first.

There is at least one company that will treat your carpet with a flea-killing powder. The powder is non-toxic to people. It is worked deeply into the carpet to prevent it from being removed by vacuuming. This treatment has proven very successful, even in the face of heavy flea infestations. However, the treatment does not address fleas in your yard. The same chemical, a form of boric acid, is also available for application by the homeowner. However, the self-application kits do not offer the year guarantee.

Yard. Yard control may also be done by professional exterminator or with various insecticides you may use yourself. Be sure that any insecticide that you use has a 30-day residual. This keeps you from having to spray every week. In climates with extended warm temperatures and high humidity, it will often be necessary to treat monthly during the warm months of the year. You should use a 30-day residual product each time. Your veterinarian is able to help you choose the most effective product for your situation.

Re-emergence of Fleas

If you recall, pre-emerged adult fleas can survive up to 140 days within the cocoon. This is significant when your pets are gone from home for extended periods of time. During the time that the house is quiet and empty, pre-emerged adults remain in their cocoon. Even if the house was treated with an insecticide, their cocoon protects them. When people and pets return to the house, adults emerge from their cocoons and immediately begin to seek a blood meal. They jump on cats, dogs, and even people. Although it may appear that a dog just returned from boarding brought fleas to your home, it is also very possible that a sudden emergence of adult fleas may account for the fleas present. If large numbers of fleas are seen, they are almost certainly newly hatched fleas and have not been brought home with the pet.

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What You Need to Know about Kittens

We would like to congratulate you on the acquisition on your new kitten. Owning a cat can be an extremely rewarding experience, but it also carries with it quite a bit of responsibility. We hope this document will give you the information needed to make some good decisions regarding your kitten.

First, let us say that we are grateful that you have chosen us to help you with your kitten's health care. If you have questions concerning any subject related to your kitten's health, please feel free to call our hospital. Either one of the technicians or one of the doctors will be happy to help you.

Introducing a New Kitten to its New Environment

A cat is naturally inclined to investigate its new surroundings. It is suggested that the cat's area of exploration be limited initially so that these natural tendencies do not create an unmanageable task. After confining the cat to one room for the first few days, you should slowly allow access to other areas of the home.

Introducing a New Kitten to Other Cats in the Household

Most kittens receive a hostile reception from other household pets, especially from another cat. The other cat usually sees no need for a kitten in the household, and these feelings are reinforced if it perceives that special favoritism is being shown the kitten. The existing cat must not feel that it is necessary to compete for food or for attention. The new kitten should have its own food and food bowl, and it should not be permitted to eat from the other cat's bowl. Although it is natural to spend time holding and cuddling the kitten, the existing cat will quickly sense that it is being neglected. The new kitten needs lots of love and attention, but the existing cat should not be slighted. In fact, the transition will be smoother if the existing cat is given more attention than normal.

The introduction period will usually last one to two weeks and will have one of three possible outcomes.

1. The existing cat will remain hostile to the kitten. Fighting may occur occasionally, especially if both try to eat out of the same bowl at the same time. This is an unlikely occurrence if competition for food and affection are minimized during the first few weeks.

2. The existing cat will only tolerate the kitten. Hostility will cease, but the existing cat will act as if the kitten is not present. This is more likely if the existing cat is very independent, has been an only cat for several years, or if marked competition occurred during the first few weeks. This relationship is likely to be permanent.

3. Bonding will occur between the existing cat and the kitten. They will play together, groom each other, and sleep near each other. This is more likely to occur if competition is minimized and if the existing cat has been lonely for companionship.

Playing Behavior in Kittens

Stimulating play is important during the first week. Stalking and pouncing are important play behaviors in kittens and have an important role in proper muscular development. If given a sufficient outlet for these behaviors with toys, your kitten will be less likely to use family members for these activities. The best toys are light weight and movable. These include wads of paper, small balls, and string or ribbon. Kittens should always be supervised when playing with string or ribbons to avoid swallowing them. Any other toy that is small enough to be swallowed should also be avoided.

Disciplining a Kitten

Disciplining a young kitten may be necessary if its behavior threatens people or property, but harsh punishment should be avoided. Hand clapping and using shaker cans or horns can be intimidating enough to inhibit undesirable behavior. However, remote punishment is preferred. Remote punishment consists of using something that appears unconnected to the punisher to stop the problem behavior. Examples include using spray bottles, throwing objects in the direction of the kitten to startle (but not hit) it, and making loud noises. Remote punishment is preferred because the kitten associates punishment with the undesirable act and not with you.

Vaccinations

There are many diseases that are fatal to cats. Fortunately, we have the ability to prevent many of these by using very effective vaccines. In order to be effective, these vaccines must be given as a series of injections. Ideally, they are given at about 6-8, 12, and 16 weeks of age, but this schedule may vary somewhat depending on several factors.

The routine vaccination schedule will protect your kitten from four diseases: distemper, two respiratory viruses, and rabies. The first three are included in a combination vaccine that is given at 6-8, 12, and 16 weeks old. Rabies vaccine is given at 16 weeks of age. Leukemia vaccine is necessary if your cat does or will go outside or if you have another cat that goes in and out since this deadly disease is transmitted by contact with other cats, especially when fighting occurs. A vaccine is also available for protection against feline infectious peritonitis (FIP); this vaccine is not necessary for all cats and is recommended in select situations.

The Need for a Series of Vaccinations

When the kitten nurses its mother, it receives a temporary form of immunity through its mother's milk. This immunity is in the form of proteins called antibodies. For about 24-48 hours after birth, the kitten's intestine allows absorption of these antibodies directly into the blood stream. This immunity is of benefit during the first few weeks of the kitten's life, but, at some point, this immunity fails and the kitten must be able to make its own long-lasting immunity. Vaccinations are used for this purpose. As long as the mother's antibodies are present, vaccinations do not "take." The mother's antibodies will neutralize the vaccine so the vaccine does not get a chance to stimulate the kitten's immune system.

Many factors determine when the kitten will be able to respond to the vaccines. These include the level of immunity in the mother cat, how much of the antibody has been absorbed, and the number of vaccines given the kitten. Since we do not know when an individual kitten will lose the short-term immunity, we give a series of vaccinations. We hope that at least two of these will fall in the window of time when the kitten has lost the immunity from its mother but has not yet been exposed to disease. A single vaccination, even if effective, is not likely to stimulate the long-term immunity which is so important.

Rabies vaccine is an exception to this, since one injection given at the proper time is enough to produce long-term immunity.

Intestinal Parasites ("Worms")

Intestinal parasites are common in kittens. Kittens can become infected with parasites almost as soon as they are born. For example, the most important source of roundworm infection in kittens is the mother's milk. The microscopic examination of a stool sample will usually help us to determine the presence of intestinal parasites. We recommend this exam for all kittens. If we can not get a stool sample, please bring one at your earliest convenience. Even if we do not get a stool sample, we recommend the use of a deworming product that is safe and effective against almost all of the common worms of the cat. Several good drugs are available. It is given now and repeated in about 3-4 weeks, because the deworming medication only kills the adult worms. Within 3-4 weeks the larval stages will have become adults and will need to be treated. Cats remain susceptible to reinfection with hookworms and roundworms. Periodic deworming throughout the cat's life may be recommended for cats that go outdoors.

Tapeworms are the most common intestinal parasite of cats. Kittens become infected with them when they swallow fleas; the eggs of the tapeworm live inside the flea. When the cat chews or licks its skin as a flea bites, the flea may be swallowed. The flea is digested within the cat's intestine; the tapeworm hatches and then anchors itself to the intestinal lining. Therefore, exposure to fleas may result in a new infection; this can occur in as little as two weeks.

Cats infected with tapeworms will pass small segments of the worms in their stool. The segments are white in color and look like grains of rice. They are about 1/8 inch (3 mm) long and may be seen crawling on the surface of the stool. They may also stick to the hair under the tail. If that occurs, they will dry out, shrink to about half their size, and become golden in color.

Tapeworm segments do not pass every day or in every stool sample; therefore, inspection of several consecutive bowel movements may be needed to find them. We may examine a stool sample in our office and not find them, then you may find them the next day. If you find them at any time, please notify us so we may provide the appropriate drug for treatment.

Feeding a Kitten

Diet is extremely important in the growing months of a cat's life, and there are two important criteria that should be met in selecting food for your kitten. We recommend a NAME-BRAND FOOD made by a national cat food company (not a generic or local brand), and a form of food MADE FOR KITTENS. This should be fed until your kitten is about 12 months of age. We recommend that you only buy food which has the AAFCO certification. Usually, you can find this information very easily on the label. AAFCO is an organization that oversees the entire pet food industry. It does not endorse any particular food, but it will certify that the food has met the minimum requirements for nutrition. Most of the commercial pet foods will have the AAFCO label. Generic brands often do not have it.

Feeding a dry, canned, or semi-moist form of cat food is acceptable. Each has advantages and disadvantages. Dry food is definitely the least expensive. It can be left in the cat's bowl at all times. If given the choice, the average cat will eat a mouthful of food about 12-20 times per day. The good brands of dry food are just as nutritious as the other forms. As a rule, most veterinarians will recommend dry food for your kitten.

Semi-moist and canned foods are also acceptable. However, both are considerably more expensive than dry food. They often are more appealing to the cat's taste; however, they are not more nutritious. If you feed a very tasty food, you are running the risk of creating a cat with a finicky appetite. In addition, the semi-moist foods are high in sugar.

Table foods are not recommended. Because they are generally very tasty, cats will often begin to hold out for these and not eat their well-balanced cat food. If you choose to give your kitten table food, be sure that at least 90% of its diet is good quality commercial kitten food.

We enjoy a variety of things to eat in our diet. However, most cats actually prefer not to change from one food to another unless they are trained to do so by the way you feed them. Do not feel guilty if your cat is happy to just eat one food day after day, week after week.

Commercials for cat food can be very misleading. If you watch carefully you will notice that many commercials promote cat food on one basis, TASTE. Nutrition is rarely mentioned. Most of the "gourmet" foods are marketed to appeal to owners who wants the best for their cats; however, they do not offer the cat any nutritional advantage over a good quality dry food, and they are far more expensive. If your cat eats a gourmet food very long, it will probably not be happy with other foods. If it needs a special diet due to a health problem later in life, it is very unlikely to accept it. Therefore, we do not encourage feeding gourmet cat foods.

Socialization

The Socialization Period for cats is between 2 and 12 weeks of age. During that time, the kitten is very impressionable to social influences. If it has good experiences with men, women, children, dogs, other cats, etc., it is likely to accept them throughout life. If the experiences are absent or unpleasant, it may become apprehensive or adverse to any of them. Therefore, during the period of socialization, we encourage you to expose your cat to as many types of social events and influences as possible.

The Litter Box

The number one behavorial problem of cats is urinating out of the litter box (inappropriate urination). There are several things that cause this frustrating problem, but some of those are related to the litter box. The following comments are included to prevent problems later because cats are particular about their litter boxes, the litter, and the location.

Choose a litter box that is large enough for your cat to fit in comfortably. It needs to be able to turn around freely. An 18 X 14 inch box with 4 inch sides is appropriate for most adult cats. Kittens may need a box with shorter sides so they can get in and out easily.

We do not recommend a box with a top (hood). Although hooded litter boxes are more private and better contain the litter, they also trap odors inside. Because cats are so fastidious, these odors often cause them to seek other places to urinate. Many cats exhibiting inappropriate urination will return to their litter boxes when the lid is removed.

There are three types of litter: clay, clumpable, and organic.

Clay litter absorbs 75-100% of its weight in moisture. This is good but not adequate to keep urine from being absorbed throughout a widespread area of litter. Solid matter and wet litter should be removed 1-2 times per day, but the entire litter box should be changed weekly. Clay litter is also quite dusty. Cats with allergies can have increased problems when breathing the litter dust.

Clumping litter is also called scoopable litter. It absorbs urine and swells to about 15 times its original volume. Therefore, you need only to remove the litter clumps; you do not need to change the entire contents of the litter box. It tends to control urine and stool odors better than clay litter.

Organic litters are made of alfalfa, newspaper, peanut hulls, corn cobs, or recycled, biodegradable materials. They appeal to many cats, but they are also not received well by others.

Some litters contain scented or odor-controlling additives. Some cats tolerate them, but others find them objectionable. To minimize the chances of inappropriate urination, it is better to avoid scented litters.

Fecal matter and wet litter need to be removed once daily for each cat that uses the litter box. Even with clumping litter, a monthly scrubbing of the litter box removes odors that may collect in the box itself. Use warm, soapy water and avoid scented disinfectants.

The location of the litter box is important. It should be on an easily cleaned surface as some cats don't always aim well. Litter is also scratched out or tracked out of the litter box frequently. It is very important that the litter box be placed in a quite, non-threatening location. Cats need their privacy and will avoid a litter box that is in a high traffic area or a location accessible to dogs.

Flea Control

Fleas do not stay on your kitten all of their time. Occasionally, they will jump off and seek another host. Therefore, it is important to kill fleas on your new kitten before they can become established in your house. Many of the flea control products that are safe on adult cats are not safe for kittens less than 4 months of age. Be sure that any flea product you use is labeled safe for kittens.

If you use a flea spray, your kitten should be sprayed lightly. Flea and tick dip is not recommended for kittens unless they are at least 4 months of age. Remember, not all insecticides that can be used on dogs are safe for cats and kittens.

There is a trick to spraying a kitten that will make the outcome safer and more successful. When a kitten is sprayed, the fleas tend to run away from the insecticide. If you spray the body first, many fleas will run to the head where they are very difficult to kill. The best method is to spray a cotton ball then use that to wipe the flea spray onto the kitten's face, from the nose to the level of the ears. That will keep you from getting it in the eyes and will cause the fleas to run down the neck toward the body. Wait about 2 minutes, then spray the body. Leave the spray on for about 3 minutes, then wipe off the excess. This will permit you to kill the most fleas while putting the least amount of insecticide on the kitten.

There are four products that are used only once per month. Program is a tablet that causes the adult fleas to lay sterile eggs. It is very effective, but it does not kill adult fleas which usually live 2-3 months. Advantage , Frontline Top Spot , and Revolution are the monthly products that kill adult fleas. They are liquids that are applied to the skin at the base of the neck. They are very effective and easy to use.

Trimming Toenails

Kittens have very sharp toe nails. They can be trimmed with your regular finger nail clippers or with nail trimmers made for dogs and cats. If you take too much off the nail, you will get into the quick; bleeding and pain will occur. If this happens, neither you nor your cat will want to do this again. Therefore, a few points are helpful:

1. If your cat has clear or white nails, you can see the pink of the quick through the nail. Avoid the pink area, and you should be out of the quick.

2. If your cat has black nails, you will not be able to see the quick so only cut 1/32" (1 mm) of the nail at a time until the cat begins to get sensitive. The sensitivity will usually occur before you are into the blood vessel. With black nails, it is likely that you will get too close on at least one nail.

3. If your cat has some clear and some black nails, use the average clear nail as a guide for cutting the black ones.

4. When cutting nails, use sharp trimmers. Dull trimmers tend to crush the nail and cause pain even if you are not in the quick.

5. You should always have styptic powder available. This is sold in pet stores under several trade names, but it will be labeled for use in trimming nails.

Ear Mites

Ear mites are tiny insect-like parasites that live in the ear canal of cats (and dogs). The most common sign of ear mite infection is scratching of the ears. Sometimes the ears will appear dirty because of a black material in the ear canal; this material is sometimes shaken out. The instrument we use for examining the ear canals, an otoscope, has the necessary magnification to allow us to see the mites. Sometimes, we can find the mites by taking a small amount of the black material from the ear canal and examining it with a microscope. Although they may leave the ear canals for short periods of time, they spend the vast majority of their lives within the protection of the ear canal. Transmission generally requires direct ear-to-ear contact. Ear mites are common in litters of kittens if their mother has ear mites.

Heartworm Infections in Cats

We are still learning about heartworms in cats. There are seven factors that need to be considered:

1. Recent studies have shown that heartworms are more common than we have thought in the past.

2. In these studies, about 25% of the cats with heartworms live indoors all of the time.

3. Heartworms are difficult to diagnose. Although we have newer and better tests than in the past, several different tests may be required for a confirmed diagnosis.

4. There is no good treatment for heartworms in cats. The drugs used in dogs are toxic to the cat, so we try to stabilize the cat and let it outlive the heartworms. This takes about 2 years.

5. Heartworm infected cats can be stable today and die suddenly tomorrow.

6. Heartworm prevention is not toxic, not expensive, and is only given once monthly. It is a chewable tablet.

We recommend that you put your cat on heartworm prevention. The monthly chewable tablet, HeartGard and the monthly topical product, Revolution , are good insurance against a disastrous disease.

Spaying Female Cats

Spaying is the removal of the uterus and the ovaries. Therefore, heat periods no longer occur. In many cases, despite of your best effort, the female will become pregnant; spaying prevents unplanned litters of kittens.

Spaying offers several advantages. The female's heat periods result in about 2-3 weeks of obnoxious behavior. This can be quite annoying if your cat is kept indoors. Male cats are attracted from blocks away and, in fact, seem to come out of the woodwork. They seem to go over, around, and through many doors. Your cat will have a heat period about every 2-3 weeks until she is bred.

It has been proven that as the female dog gets older, there is a significant incidence of breast cancer and uterine infections if she has not been spayed. Spaying before she has any heat periods will virtually eliminate the chances of either. There is mounting evidence to believe that this is also true of cats. If you do not plan to breed your cat, we strongly recommend that she be spayed before her first heat period. This can be done anytime after she is 5 months old.

Neutering Male Cats

Neutering is the surgical removal of both testicles. It offers several important advantages. Male cats go through a significant personality change when they mature. They become very possessive of their territory and mark it with their urine to ward off other cats. The tom cat's urine develops a very strong odor that will be almost impossible to remove from your house. They also try to constantly enlarge their territory which means one fight after another. Fighting results in severe infections and abscesses and often engenders rage in your neighbors. We strongly urge you to have your cat neutered at about 6 to 9 months of age. If he should begin to spray his urine before that time, he should be neutered immediately. The longer he sprays or fights, the less likely neutering is to stop it.

Breeding Cats

If you plan to breed your cat, she should have at least one or two heat periods first. This will allow her to physically mature allowing her to be a better mother without such a physical drain on her. We do not recommend breeding after 5 years of age unless she has been bred prior to that. Having her first litter after 5 years of age is more physically draining to her and increases the chances of her having problems during the pregnancy and/or delivery. Once your cat has had her last litter, she should be spayed to prevent the female problems older cats have.

Neutralizing Destructive Behavior with the Claws

There are four options that you should consider: frequent nail clipping, nail shields, surgical declawing, and tendonectomy.

The nails may be clipped according to the instructions above. However, your cat's nails will regrow and become sharp again in about 4-7 days. Therefore, to protect your property, it will be necessary to clip them one to two times per week.

There are some commercially available products that are called nail caps. The most common one is called Soft Paws . These are generally made of smooth plastic and attach to the end of the nail with a special glue. The nails are still present, but the caps prevent them from causing destruction. After 2-4 weeks the nails will grow enough that the caps will be shed. At that time, you should be prepared to replace them.

Surgical declawing is the removal of the nail at its base. This is done under general anesthesia; there is very little post-surgical discomfort, especially when it is performed on a kitten. Contrary to the belief of some, this surgery does not cause lameness or psychological damage. Actually, a declawed cat will not realize the claws are gone and will continue to "sharpen" the claws as normal without inflicting damage to your furniture. This surgery can be done as early as 12 weeks of age or anytime thereafter. It can also be done the same time as spaying or neutering. Once declawed, your cat should always live indoors since the ability to defend itself is compromised.

Tendonectomy is the surgical removal of a small part of the tendon on the bottom of each toe. This tendon is needed to make the nail extend. The cat retains its nails, but it cannot extend them for sharpening and scratching. The only disadvantage of this procedure is that the nails continue to grow and may grow into the pads. Therefore, the nails should be clipped every 7 to 14 days.

Pet Identification

The latest in pet retrieval is microchipping. This tiny device is implanted with a needle so the process is much like getting an injection. Our scanner can detect these chips; humane societies and animal shelters across the country also have scanners. A national registry permits the return of microchipped pets throughout the United States and Canada. We recommend it.

Blood Typing

Blood typing is available for cats. This is important should your cat develop anemia (decreased numbers of red blood cells) due to a disease or becomes anemic due to blood loss. It needs to be performed only once in your cat's lifetime.

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Inappropriate Elimination Disorders in Cats

The term "elimination disorder" is used to describe cats that do not use their litter boxes for urination and/or defecation; instead, these cats eliminate somewhere in the house. Elimination disorders are the most common behavioral problem of cats. Because most owners take pride in their homes, house soiling by the cat can strain the owner-pet relationship to the breaking point. Unfortunately, in some cases, frustrated owners give up their cat to an animal shelter or elect for euthanasia.

Contributing Factors

In some cases, a medical problem can be related to inappropriate elimination. When this is the case, improvement can be expected if the medical cause can be successfully treated. In most cases, however, inappropriate housesoiling is primarily a behavioral problem.

Prevalence

A recent study performed by an animal behaviorist at the University of Pennsylvania reported that 40 to 75% of all cats presented with behavior problems had an elimination disorder. It appears that longhaired cats are over-represented as compared to shorthaired cats. This has not been completely evaluated but may be related to adherence of certain types of litter to the longer fur.

Causes

As mentioned above, after medical causes of these problems have been ruled out, the source of the problem is considered a behavioral disorder. Behavioral causes of inappropriate elimination fall into two general categories: 1) a dislike of the litter box, and 2) stress-related misbehavior.

One of the main reasons for the cat avoiding the litterbox is because the box has somehow become objectionable to the cat. This usually occurs because it is not cleaned frequently enough or because the cat objects to the type of litter used; this is called substrate aversion. Sometimes, the cat is dislikes the location of the litterbox (avoidance of location). Substrate aversion is by far more common than avoidance of the box because of its location.

There are many possible related causes. Some of these can include the following:

1. A new person (especially a baby) in the house

2. A person that has recently left the house (permanently or temporarily)

3. Several new pieces of furniture or rearrangement of existing furniture

4. New drapes or carpet

5. Moving to a new house

6. A new pet in the house

7. A pet that has recently left the house

8. A new cat in the neighborhood that can be seen by the indoor cat

9. A cat in heat in the neighborhood

10. A new dog in the neighborhood that can be heard by the indoor cat

Therapy

Most successful treatments rely on a combination of behavior modification techniques and drug therapy.

A. Behavior Modification

Behavior therapy involves a dual approaching involving (1) Aversion Therapy and (2) Attraction Therapy. The former repels the cat from the inappropriate location, and the latter encourages the cat to choose an appropriate location.

The purpose of Aversion Therapy is to make the area of inappropriate urination or defecation undesirable for the cat. There are many ways to do this, but the following steps have proven successful in a high percentage of cases.

1. A product to neutralize the odor of urine or stool should be used in places where inappropriate urination or defecation has occurred. Although many of the available products do a good job, none of them will undo months or years or repeated soiling. The sooner the affected area is treated, the better. If the objectionable location is on carpet, it is necessary to treat the carpet and the pad below because most of the odor will be in the pad. This usually means soaking the carpet with the neutralizing product so it penetrates into the pad. Test an inconspicuous piece of carpet for staining before using any odor neutralizing product.

2. If the soil in potted plants is being used, place a lemon-scented air freshener at the base of the plant. This will usually repel the cat. In some cases, the plant may need to be removed.

3. Cover the area(s) with aluminum foil and secure it to the carpet or furniture with masking tape. Aluminum foil is a surface on which most cats will not walk.

The purpose of Attraction Therapy is to make the litter box more desirable than the inappropriate site. The following are usually successful:

1. Purchase a new litter box; even well-cleaned litter boxes have odor deep in the plastic. Although we like our privacy, most cats find a hooded litter box undesirable presumably because it traps odors inside. Occasionally, a very shy or timid cat will prefer a covered litterbox.

2. Purchase non-scented clumping litter. If your cat has not been using this type of litter, it will usually find it more desirable than the clay types. In generally, most cats seem to prefer these newer litters because they are softer. Some behaviorists theorize that these new litters are more reminiscent to the cat's ancestral elimination substrate - desert sand.

3. Place the new litter box near the area of inappropriate urination until it is used for several days, then move it 2-3 feet (0.7-1 m) per day back to the desired location.

4. Keep the existing litter box in the normal location in case the aversion therapy causes your cat to return to it.

B. Medical Therapy

This usually involves one of three types of medications.

1. Anti-depressants, including amitriptyline and buspirone

2. Tranquilizers, including diazepam and phenobarbital

3. Hormones, including megestrol acetate and medroxyprogesterone acetate

While none of the oral medications have been approved for use on cats, most have been in use long enough to give us reason to believe that they are very safe.

Buspirone (trade name Buspar ) is an anti-anxiety drug prescribed by physicians; it is a human drug, not a veterinary drug. It has been shown to be effective in a significant number of cats with elimination behavior problems.

Its success rate is not 100% but, for the intended purpose, it has been shown to be more effective than many of the other drugs.

The following outline should be followed. If the sequence is not clear, please call for further instructions.

1. Give 5 mg (1 tablet) twice daily for 1 week

a. If there is no response, give 7.5 mg (1 1/2 tablets) twice daily for one week

1) If there is no response, discontinue buspirone.

2) If there is good response, give 5 mg twice daily for 8 weeks.

b. If there is good response, give 5 mg twice daily for 8 weeks.

2. If a relapse occurs after successful therapy, resume buspirone at a dose of 5 - 7.5 mg twice daily and continue for 6-12 months.

C. Another Option

Recently, a pharmaceutical company introduced an aerosol spray that can be used in the area of appropriate elimination. The solution contains a synthetic derivative of feline hormones, called pheromones. It is thought to have a calming and comforting effect on some cats. It has not been completely studied by independent researchers but is thought to show some promise in decreasing, though not totally eliminating, inappropriate elimination in cats.

Prognosis

The prognosis for improvement is more likely if several of the following are true:

1. The duration is less than 1 month when treatment begins.

2. There are only one or two locations in the house that the cat uses for inappropriate elimination.

3. It is possible to identify and relieve the stress-causing situation.

4. It is possible to neutralize the odor caused by the urine or stool.

5. You have only one cat.

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Feline Leukemia Virus Diseases

Feline leukemia virus infection was, until recently, the most common fatal disease of cats. Because we can now protect cats with a leukemia virus vaccine, we are seeing fewer cases of the disease. However, it still remains a major cause of death in cats.

"Leukemia" means cancer of the white blood cells. This was the first disease associated with the feline leukemia virus (FeLV) and, thus, the source of its name. We often use the term "leukemia" rather loosely to include all of the diseases associated with the virus, even though most are not cancers of the blood. This virus causes many other fatal diseases, in addition to leukemia.

Feline leukemia virus is classed as a retrovirus. The retroviruses are of particular importance because they have the ability to integrate into the genetic material, or DNA, of the host. For this reason, some call the retroviruses "the ultimate genetic parasites". There are three subtypes of the virus and the diseases caused are dependent upon the particular subtype involved. The feline immunodeficiency virus, or feline AIDS virus, is another feline retrovirus. In humans, HIV is caused by a retrovirus.

Contributing Factors

Cats who are greatest risk for contracting the feline leukemia virus are those who live in close, direct contact with an infected cat. Fighting is a known risk factor because the virus is shed in saliva. Kittens may contract the virus from the mother via the placenta.

Prevalence

In the total population of cats, the incidence of FeLV is only about 1-2%. Free-roaming adult cats that are FeLV-negative have usually acquired age-related resistance to the virus. The incidence is much higher in "exposure households", or households where there is a FeLV-positive cat living among other cats. In this setting, 30% - 100% of the cats may be found to test positive.

Clinical Signs

There are three major disease categories associated with the FeLV:

1) Leukemia is a cancer of the white blood cells.

2) Lymphosarcoma (also called Lymphoma) is a cancer of many different organs but it begins in lymphoid tissue, such as a lymph node. Almost any tissue may be affected; organs commonly involved include lymph nodes, intestinal tract, kidneys, liver, spinal cord, brain, bone marrow and blood. In young cats, lymphoma often manifests as a mass within in the thoracic cavity; this is called "mediastinal lymphoma".

3) The Non-Cancerous Diseases include a variety of somewhat unrelated diseases. Anemia, abortion, arthritis, and immune suppression are examples. When the immune system is suppressed, the cat becomes susceptible to many diseases it would ordinarily resist and mild diseases, such as respiratory infections, may become fatal.

Causes/Transmission

The main means of transmitting the virus is through cat fights. Because large quantities of the FeLV are shed in cat saliva, puncture wounds associated with fighting result in injection of the virus into other cats. There are also large amounts of virus in respiratory secretions. Other less frequent routes of viral spread include sharing food and water bowls, cats grooming each other, and transmission from mother to kittens before birth.

Diagnosis

The "leukemia test" is used to determine if a cat harbors the virus. Any of three different tests may be used to detect one particular virus protein in the cat. Some tests detect earlier stages of infection, whereas others are used to detect later (ie., irreversible) stages of infection.

1. The blood ELISA test is performed on a blood sample and detects the FeLV at any stage of infection. This test turns positive within a few days of infection and, in some cases, may later turn negative if the cat's immune system eliminates the infection.

2. The IFA test is performed on a blood smear and turns positive only after the FeLV infection has progressed to a late stage of infection. Once positive, the IFA test usually means that the cat has a permanent infection. A cat that tests IFA positive is only rarely able to successfully eliminate the virus. The cat that is IFA positive is called "persistently positive" or "persistently viremic".

3. The tears/saliva ELISA test is performed on a sample of tears or saliva. It turns positive only in a late stage of infection; therefore, it may yield a false negative result in cats that are in the early stage of FeLV infection. It also has been associated with some false positive results due to inherent errors in the way the test is performed. Because of these problems, the tears and saliva tests are not used routinely.

The Cat that Tests Positive - Possible Outcomes of FeLV-infection

When we are exposed to a virus, such as a flu virus, there are two possible outcomes. Either our immune system responds to the challenge and protects us, or it is unable to respond successfully and we develop the flu. A number of factors determine which outcome occurs and whether or not we will get sick:

1. The amount of the virus (Did someone sneeze directly in your face?)

2. The strain of the virus (Some strains are more potent than others.)

3. The status of our immune system (Are immune suppressing drugs being taken?)

4. Age (The very young and very old are more likely to become infected.)

5. The presence of other infections which might cause debilitatioin

The behavior of the feline leukemia virus in the cat's body cannot be predicted. Instead of the two possible outcomes described above (ie., we get sick or we get well), there are four possible outcomes for cats with FeLV. Understanding these allows one to more fully comprehend some of the unusual situations that may arise in cats.

OUTCOME 1: IMMUNITY The cat mounts an immune response, eliminating the infection.

This is the most desired outcome because it means that the cat will not become persistently infected with the virus. During this period of virus challenge, the cat may actually develop a mild form of illness. Fever, poor appetite, lethargy, and swollen glands (lymph nodes) in the neck may develop and last for 3 to 10 days. Outcome 1 occurs about 40% of the time after a cat is challenged by the FeLV. Immunity to the virus is more likely to develop in the adult cat than in the kitten.

OUTCOME 2: INFECTION The cat's immune system is overwhelmed by the virus.

This is the least desired outcome because the cat is persistently infected with FeLV. All three of the FeLV tests will become positive and remain positive for the rest of the cat's life.

Although the cat may be sick for a few days initially (as described above), it usually recovers and appears normal for weeks, months, or years. Ultimately, most of these cats die of FeLV-related disease, but as many as 50% will still be healthy after 2-3 years and 15% after 4 years. Vaccination of these cats will not cause any problems, but doesn't help the cat, either.

Outcome 2 occurs about 30% of the time after a cat is challenged by FeLV. Although infection is more likely to occur in the kitten, many cats are persistently infected as adults. Although the main mode of viral transmission is through bite wounds (saliva), direct daily contact with a FeLV infected cat will often result in transmission of the virus. Non-infected exposed cats are at risk and should be vaccinated, although daily viral contact will result in vaccination failure of some cats.

OUTCOME 3: LATENCY The cat harbors the virus but we cannot easily detect it.

Unlike other viruses, the FeLV does not directly kill the cat's cells or make them become cancerous. Instead, it inserts a copy of its own genetic material (called DNA) into the cat's cells; these cells may later be transformed into cancer cells or cells which will no longer function normally. In Outcome 3, the genetic change in the cat's cells will remain undetected for an average of 2 1/2 years, during which time the cat will appear completely normal.

In the early stages of infection, the blood ELISA test will be positive, but it will turn negative about 2-4 weeks later. Following that, the blood ELISA and the IFA tests will remain consistently negative.

The prospect of latent infection presents us with a frustrating situation. Latency is estimated to occur about 30% of the time; it leaves the cat in a precarious situation. Some cats will ultimately reject the abnormal cells, and the state of latency will be terminated. In other cats these abnormal cells will result in the production of new FeLV which will result in Outcome 2. Outcome 2 generally leads to death due to a FeLV disease.

Latency is the state that explains the following situations.

1. Latently infected cats will test negative on all of the FeLV tests. If they are vaccinated, they will not be protected. They may develop a fatal FeLV-related disease later, especially following some form of stress or the administration of steroids. Stressors that may activate latent infections include pregnancy and nursing, overcrowding, movement to a new environment, territorial conflicts, poor nutrition, and other diseases. Steroids are used commonly in cats because they are very beneficial for many feline diseases

2. Lymphosarcoma is the form of cancer normally caused by the FeLV. Cats some forms of lymphosarcoma normally test positive with any FeLV test. Latently infected cats may have lymphosarcoma and test negative on the FeLV tests. It is also thought that some cats successfully eliminate the virus but not before malignant transformation of cells has already occurred. This may be another explanation for FeLV-negative cats with lymphosarcoma.

3. Latently infected pregnant cats may test FeLV negative (and even be vaccinated) but pass the FeLV to their kittens through nursing. These kittens often experience Outcome 2.

OUTCOME 4: IMMUNE CARRIER The cat becomes an immune carrier.

The FeLV becomes hidden in some of the cat's epithelial cells. Although the FeLV is multiplying, it is not able to get out of these cells because the cat is producing antibodies against the virus. The cat will appear normal in every way, except for its test results. The immune carrier will have a positive blood ELISA test and a negative IFA test.

This situation is unlikely to happen; it is estimated to occur 1-2% of the time. These cats may revert to an active FeLV infection (Outcome 2) or may develop a latent infection (Outcome 3). The main reason for understanding this situation is that it explains conflicting FeLV test results. Otherwise, there is not a specific test to detect it.

Treatment

Leukemia. Some forms of leukemia (blood cancer) are unresponsive to all available forms of cancer treatment. Other types of leukemias may respond to chemotherapy, though most of these have an average survival time of less than one year. Because the virus is not affected by treatment, the cat will always remain infected with FeLV. Also, relapse of leukemia is possible (and expected). These factors cause us to recommend treatment of leukemia in very few situations.

Lymphosarcoma. Lymphosarcoma is treatable, but not curable. Research has shown that cats with lymphoma who are FeLV-positive do not respond to treatment as well as FeLV-negative cats.

Secondary infections. Depending upon the type of infection involved and the general state of the cat's health, the prognosis may range from favorable to guarded. For example, bacterial infections may respond well to antibiotic therapy. Other types of infections, such as certain fungal infections, may not respond well because of the FeLV-induced weakness of the cat's immune system.

The healthy FeLV-positive cat. Healthy infected cats may remain apparently unaffected by the virus for several years. With good supportive care and prompt attention to all potential medical problems, these cats may live for a number of years. Bear in mind that these cats should be considered infectious and potentially dangerous to other cats. Such cats should be isolated from non-infected cats to prevent spread of infection. Many people find this undesirable or impossible and elect euthanasia to protect non-infected cats.

Prognosis

The prognosis is dependent upon many factors. In general, 80% of all persistently positive cats (IFA positive) succumb within three years, most of these deaths occurring within the first six months of detection. The cat who is transiently positive may expect a normal lifespan, or may become ill if latent virus in the body is reactivated.

Transmission to Humans

Extensive tests have been conducted for over 15 years to determine if the FeLV can be transmitted to humans. To date, no conclusive evidence has demonstrated any FeLV-related disease in humans or other animal species, including the dog. However, persons with compromised immune systems are of concern to many researchers. Newborn babies, persons on chemotherapy, AIDS patients or transplant recipients on anti-rejection drugs should probably not be unnecessarily exposed to this or any other virus.

Prevention

A vaccine is available to protect cats from the FeLV. Although not 100% of cats are totally protected, the vaccine is strongly recommended for cats who are exposed to open populations of cats, (ie., outdoor cats). We have seen a definite decline in the incidence of feline leukemia virus infection and related diseases since vaccine use became widespread. We strongly recommend it for cats at risk of exposure. If your cat stays indoors at all times and is not in contact with another cat that goes outdoors, the vaccine is generally not recommended. Many owners have concern that the vaccine will cause a cat to test positive for the virus, but this is not true. While the history of vaccination is important for us to know, it does not alter our ability to interpret the feline leukemia virus test.

Testing Prior to Vaccination

Cats that are already infected with the FeLV will not be helped by the vaccine. (They will not be hurt by it, either). We recommend pre-vaccination testing for the FeLV in these particular situations:

1) Cats with a history of cat fights or fight wounds (ie., abscesses)

2) Cats exposed to FeLV-infected cats

3) Cats from unknown backgrounds (particularly animal shelters, humane societies, or pet shops)

4) Routine health care, especially in multicat household.

Injection Site Sarcomas

In recent years, a disturbing phenomenon has been identified by veterinary researchers. A relationship has been found between feline leukemia virus vaccine (as well as rabies vaccine) and the development of very aggressive tumors at the injection site. The numbers of cats who have developed these tumors is very small compared to the total number of vaccinations given (1-3 per 10,000), but the outcome is devastating for cats that do get these cancers. Several veterinary schools are actively researching this problem. It remains unclear exactly why some cats develop tumors in response to vaccination; a genetic predisposition is thought to be part of the problem. At this time, feline specialists are recommending that leukemia vaccination be reserved for cats that are at risk for exposure to the virus. Strictly indoor cats generally do not need vaccination against FeLV. We can advise you about exceptions to the routine vaccination protocols.

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Feline Infectious Anemia
(Hemobartonellosis)

Feline Infectious Anemia (FIA) is a blood disease of cats caused by a microscopic parasite called Hemobartonella felis (H. felis). Because of the organism's name, this disease is also sometimes called hemobartonellosis. This organism attaches to the surface of the cat's red blood cells, where its presence is eventually detected by the immune system. Once the immune system recognizes the parasite, it attempts to eliminate it by destroying the red blood cells. With destruction of a large number of red cells, anemia may result.

Contributing Factors

Identified risk factors for FIA include anemia, positive feline leukemia virus (FeLV) status, positive feline immunodeficiency virus (FIV) status, access to the outdoors, a history of cat-fight wounds, and lack of vaccinations. Male cats are probably at greater risk.

Cats with FIA should be screened for the presence of immunosuppressive viruses. The primary viruses are FeLV and the FIV. These viruses can serve as stresses which promote development of FIA. If one or both of the viruses is found, the prognosis for recovery is more unpredictable than in the virus-negative cat.

Prevalence

The true prevalence of the disease is unknown because of the difficulty in identifying the organism and its inconsistent presence in the bloodstream. The prevalence is higher in sick cats than in healthy cats. Estimates of its presence in sick cats ranges from 0 - 28% of cats examined.

Clinical Signs

Reported clinical signs include depression, weakness, jaundice, weight loss, anemia, enlargement of the spleen, and death.

Causes/Transmission

Although the method of transmission has not been conclusively demonstrated, it is thought to be spread between cats by blood-sucking insects and, possibly, by wounds from cat fights. Experimentally, the organism has been transmitted between cats by blood transfusion. Newborn kittens may be infected, but it has not been proven if the infection is established through the placenta, during birth, or by nursing the mother.

Diagnosis

Because H. felis can be found on the red blood cells of healthy cats, detection of the organism does not always equate with a diagnosis of FIA. In many cases of FIA, the cat has a concurrent disease or another form of stress. This state of debilitation then triggers H. felis and allows the development of FIA.

Diagnosis of this disease is made from a fresh blood smear which is stained and examined microscopically. If the cat is anemic and large numbers of H. felis are present, the diagnosis of FIA is made. Unfortunately, H. felis is not always present on the cat's red blood cells because it appears in the blood stream in cycles. If FIA is suspected, it may be necessary to examine several blood samples before H. felis is identified.

Treatment

Treatment is relatively simple and usually successful. Most often, medications in the tetracycline family are used. The drugs are not expected to clear the organism completely but, instead, suppress it's replication in the cat's body.

Additional treatments may involve a blood transfusion for severely anemic cats, as well as prednisone for temporary suppression of immune-destruction of the red blood cells.

Prognosis

If treatment is not initiated in the acute phase, up to one-third of all cats with FIA will die. Cats who recover from the early stages of the disease will become chronic carriers of the organism and are thought to be susceptible to relapse with periods of stress or illness. With chronic infection, it may be impossible to detect the organism in the blood because it is present in such low numbers.

Transmission to Humans

This disease is not transmitted to humans.

Prevention

Although there is no way to prevent the disease, chances of contracting the disease may be lessened by keeping cats indoors, preventing fight wounds, providing appropriate vaccination against other diseases, and controlling fleas and ticks.

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Frequently Asked Questions